Antioxidant Activity, Toxicity Effect and Phytochemical Screening of Some Brown Algae Padina australis Extracts from Dutungan Island of South Sulawesi Indonesia

Brown algae is one of the bioactive compound sources producing secondary metabolites as antioxidant. Padina australis is a brown algae (Phaeophyceae) specific in Dutungan island Barru, South Sulawesi suspected of secondary metabolic compound. This study aims to determine the level of toxicity and antioxidant active compounds of Padina australis. Extraction of active compounds in P.australis was carried out by maceration method using a solven of methanol, ethyl acetate, and n-hexane. Each extract was tested for its toxicity against Artemia salina L and DPPH as radicals. The results showed that the toxicity test of methanol, ethyl acetate, and n-hexane extract against A. salina L obtained LC50 values, respectively 785.03 ppm, 73.3 ppm and 300 ppm. Antioxidant activity of methanol, ethyl acetate and n-hexane extract with IC50 values at 446.88 ppm, 259.48 ppm, and 495.67 ppm.