Antimicrobial Activity and Sulfated Polysaccharides Antibiofilms in Marine Algae Against Dental Plaque Bacteria: A Literature Review

Introduction: Biofilm in dental plaque is known to become the cause of the occurrence of dental fection in the oral cavity, one of which is caries. A biofilm is a community of certain microorganisms attached to
the surface, which is generally encapsulated and protected by an extracellular matrix consisting of various biopolymers. Therefore, the elimination of microbial biofilms is not easy, and its existence shows
resistance to antimicrobial. Therefore, it needs an agent of antipyretic in the form of antimicrobial and antibiofilm that can prevent the presence of biofilm formation in dental plaque. Objective: To see the activities of antimicrobial and antibiofilm of sulfated polysaccharides marine algae against dental plaque bacteria. Method: Scientific evidence and clinical cases were taken from literature to support this review and information about the relationship of teeth to the incidence of stunting in children was collected.
Results/Discussion: Marine algae have bioactive compounds with their potential to act as antimicrobial agents and antibiofilm for oral pathogens that cause oral infections in the human body. Conclusion: Fucoidans content in several types of marine algae are classified as Sulfated Polysaccharides that are effectively working as an antimicrobial and antibiofilm