Antibacterial Chitosan of Milkfish Scales (Chanos Chanos) Onbacteria Prophyromonas Gingivalis & Agregatibacter Actinomycetemcomitans

Antibacterial Chitosan of Milkfish Scales (Chanos Chanos) Onbacteria Prophyromonas Gingivalis & Agregatibacter Actinomycetemcomitans Context: This research was conducted to appear the effectiveness of milkfish scales chitosan gel (Chanos Chanos) on the inhibition of Aggregatibacter actinomycetemcomitans which is a pathogenic bacterium that causes periodontitis. This research was conducted with five treatments with five repetitions, five treatments, namely: Positive control (metronidazole), negative control (aquadest), chitosan gel in milkfish scales concentration of 1%, 5%, and 10%. This research measuring instrument uses a calipers in units of millimeters (mm). Based on the results of the Mann Whitney test, there was a significant difference in inhibition of chitosan gel in 1%, 5%, and 10% milkfish gel against Aggregatibacter actinomycetemcomitans bacteria (p <0.005), and based on the Kruskal Wallis test it was found that the higher concentration of milkfish scale then the higher the average inhibition power. It was concluded that milkfish scales gel chitosan (Chanos chanos) can inhibit the growth of Aggregatibacter actinomycetemcomitans and the higher the concentration of chitosan gel in milkfish scales, the higher the inhibitory zone produced.