Health promoting benefits of pongamol: An overview


Shamima Jahan, - and Md. Hasan Mahmud, - and Zidan Khan, - and Ashraful Alam, - and Anees Ahmed Khalil, - and Abdur Rauf, - and Abu Montakim Tareq, - and Firzan Nainu, - and Syed Mohammed Tareq, - and Talha Bin Emran, - and Muneeb Khan, - and Ishaq N. Khan, - and Polrat Wilairatana, - and Mohammad S. Mubarak, - (2021) Health promoting benefits of pongamol: An overview. Elsevier.

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Abstract (Abstrak)

Plant-derived chemicals are a source of novel chemotherapeutic agents. Throughout the human civilization, these novel chemicals have led to the discovery of new pharmacological active agents. Research on herbal medicine is of great importance, as most of the active agents used for treating numerous diseases are from natural sources, while other agents are either semisynthetic or synthetic. Pongamol, a flavonoid, which is the main constituent of Pongamia pinnata, is one such active agents, which exhibits diverse pharmacological activities. Various in vivo and in vitro studies revealed that pongamol is a potentially active agent, as it exerts anticancer, anti-inflammatory, antioxidant, antimicrobial, and anti-diabetic activities. Accordingly, the aim of the present review was to give an up-to-date overview on the chemistry, isolation, bioavailability, pharmacological activity, and health benefits of pongamol. This review focuses on the medicinal and health promoting activities of pon gamol, along with possible mechanisms of action. For this purpose, this review summarizes the most recent literature pertaining to pongamol as a therapeutic agent against several diseases. In addition, the review covers information related to the toxicological assessment and safety of this phytochemical, and highlights the me dicinal and folk values of this compound against various diseases and ailme

Item Type: Article
Subjects: R Medicine > RS Pharmacy and materia medica
Depositing User: - Andi Anna
Date Deposited: 28 Sep 2021 03:22
Last Modified: 28 Sep 2021 03:22
URI: http://repository.unhas.ac.id:443/id/eprint/7187

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