Analisis Determinan Kualitas Hidup Pasien Penyakit Jantung Koroner Di RSUP Dr Wahidin Sudirohusodo Makassar 2025

Hardiyanti Nur. Analisis Determinan Kualitas Hidup Pasien Penyakit Jantung Koroner Di RSUP Dr Wahidin Sudirohusodo Makassar 2025 (Dimbing oleh Andi Zulkifli dan Ridwan Amiruddin) Latar Belakang. Penyakit jantung koroner (PJK) adalah kondisi kardiovaskular utama dan menyumbang sekitar 35% dari total kematian global. Di Asia Tenggara, PJK menempati urutan teratas sebagai penyebab kematian, dengan angka kematian kasar (AKK) sebesar 104 per 100.000 penduduk. Beban PJK diperkirakan akan meningkat, terutama di negara-negara berkembang, termasuk Indonesia. Menurut Kementerian Kesehatan Indonesia (2023), penyakit kardiovaskular merupakan pengeluaran terbesar dalam sektor kesehatan di negara ini, dengan 20.037.280 kasus yang tercatat. PJK secara signifikan memengaruhi fungsi harian pasien akibat gejala yang persisten dan persepsi individu tentang penyakit, yang berpotensi merusak kualitas hidup terkait kesehatan (HRQoL). Selain keterbatasan fisik, PJK juga dapat memengaruhi kesejahteraan psikologis dan spiritual secara negatif. Tujuan. Mengidentifikasi faktor-faktor penentu yang terkait dengan kualitas hidup terkait kesehatan pada pasien dengan PJK. Metode. Desain studi yang digunakan adalah studi kasus-kontrol. Populasi penelitian terdiri dari pasien rawat jalan yang terdaftar di Pusat Jantung Terpadu Rumah Sakit Umum Dr. Wahidin Sudirohusodo, Makassar. Sebanyak 142 peserta dipilih menggunakan teknik purposive sampling. Persetujuan etik diperoleh dari Komisi Etik Penelitian Kesehatan Masyarakat, dan semua peserta memberikan persetujuan tertulis yang diinformasikan. Analisis statistik dilakukan untuk menguji hubungan antara determinan potensial dan hasil kualitas hidup. Hasil. Hasil penelitian menunjukkan ada hubungan antara gaya hidup (p=0,000), aktivitas fisik (p=0,000), kepatuhan minum obat (p=0,000), stres (p=0,005), depresi (p=0,016) dan intervensi jantung (p=0,000) dengan kualitas hidupa pasien PJK dan tidak ada hubungan antara cemas (p=0,207) dengan kualitas hidup pasien PJK. Kesimpulan. Ada hubungan yang bermakna antara gaya hidup, aktivitas fisik, kepatuhan minum obat, stress, depresi, dan intervensi jantung dengan kualitas hidup pasien PJK di RSUP dr Wahidin Sudirohusodo Makassar. Hardiyanti Nur. Determinants of health-related quality of life among patients with coronary heart disease at Dr. Wahidin Sudirohusodo General Hospital Makassar 2025 (Supervised by Andi Zulkifli and Ridwan Amiruddin) Background. Coronary heart disease (CHD) is a major cardiovascular condition and accounts for approximately 35% of total global mortality. In Southeast Asia, CHD ranks as the leading cause of death, with a crude death rate (CDR) of 104 per 100.000 population. The burden of CHD is projected to increase, particularly in developing countries, including Indonesia. According to the Indonesian Ministry of Health (2023), cardiovascular diseases represent the highest healthcare expenditure in the country, with 20.037.280 reported cases. CHD significantly affects patients’ daily functioning due to persistent symptoms and individual illness perceptions, thereby potentially impairing health-related quality of life (HRQoL). Beyond physical limitations, CHD may also negatively influence psychological and spiritual well-being. Aim. Identify determinants associated with health-related quality of life among patients with coronary heart disease. Method. A case–control study design was employed. The study population comprised outpatients registered at the Integrated Cardiac Center of Dr. Wahidin Sudirohusodo General Hospital, Makassar. Purposive sampling was used to recruit 142 participants. Ethical clearance was granted by the Public Health Research Ethics Commission, and written informed consent was obtained from all participants. Statistical analyses were conducted to examine associations between potential determinants and quality of life outcomes Result. Significant associations were found between lifestyle (p < 0.001), physical activity (p < 0.001), medication adherence (p < 0.001), stress (p = 0.005), depression (p = 0.016), and cardiac intervention history (p < 0.001) with health-related quality of life among CHD patients. No significant association was observed between anxiety and quality of life (p = 0.207). Conclusion. Lifestyle factors, physical activity, medication adherence, stress, depression, and history of cardiac intervention were significantly associated with health-related quality of life among patients with coronary heart disease at Dr. Wahidin Sudirohusodo General Hospital, Makassar. These findings highlight the importance of comprehensive clinical and psychosocial management strategies to improve quality of life outcomes in CHD patients.