Bromelain a Potential Bioactive Compound: A Comprehensive Overview from a Pharmacological Perspective

Bromelain is an effective chemoresponsive proteolytic enzyme derived from pineapple
stems. It contains several thiol endopeptidases and is extracted and purified via several methods. It
is most commonly used as an anti-inflammatory agent, though scientists have also discovered its
potential as an anticancer and antimicrobial agent. It has been reported as having positive effects
on the respiratory, digestive, and circulatory systems, and potentially on the immune system. It
is a natural remedy for easing arthritis symptoms, including joint pain and stiffness. This review
details bromelain’s varied uses in healthcare, its low toxicity, and its relationship to nanoparticles.
The door of infinite possibilities will be opened up if further extensive research is carried out on this
pineapple-derived enzyme.