Hematological and Biochemical Profile of Bali Cattle Affected by Foot and Mouth Disease at Different Infection Stages

| Foot and Mouth Disease (FMD) has an adverse effect on numerous animals with cloven hooves, including cattle, sheep, goats, buffalo, pigs, etc. Therefore, this study aimed to examine hematological and biochemical profile of cattle, based on different stages of FMD infection. A total of 24 blood samples were collected from Bali cattle, then grouped into 4, based on the estimated age of lesion inflicted on the animals: Group A (no lesions), Group B (early stage), Group C (advanced stage), and Group D (recovery stage). The results showed that the white blood cell and granulocyte count in Group B was significantly higher than in Group A, while the lymphocyte and mid-cell count in Group B were higher compared to the other groups. The concentration of hemoglobin and hematocrit in Group A was significantly higher compared to the other groups. In contrast, the mean corpuscular volume and mean corpuscular hemoglobin in Group A were significantly higher compared to Groups B and C. The serum concentration of albumin in Group A was significantly higher than in other groups, and the serum concentration of aspartate aminotransferase in Group D was higher than in the other groups. The serum concentrations of creatinine and blood urea nitrogen in Group A were significantly higher than in Groups C and D. In conclusion, hematological and biochemical profile of FMD-infected cattle differed during early, advanced, and recovery stages. Therefore, the treatment of FMD among various stages of infection must be considered.