IWAN DINI, NUNUK HARIANI SOEKAMTO, FIRDAUS, UNANG SUPRATMAN & JA (2022) Alkaloid Caulerpin and Cytotoxic Activity against NCLH460 Lung Cancer Cells Isolated along with β-sitosterol from the Halimeda cylindracea Decaisne = Alkaloid Kaulerpin dan Aktiviti Kesitotoksikannya terhadap Sel Barah Paru-Paru NCL-H460 Dipencilkan bersama β-sitosterol daripada Halimeda cylindracea Decaisne. Sains Malaysiana 50(9)(2021): 2663-2674.
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Abstract (Abstrak)
Alkaloid caulerpin (1), along with β-sitosterol (2), were isolated from the n-hexane extract of the macroalga Halimeda cylindracea Decaisne. The chemical structure was identified by a spectroscopic method including IR, MS, UV, NMR 1D, NMR 2D, and comparison with data of spectra previously reported. Compounds (1) and (2) were isolated for the first time from this macroalga. Compund (1) were evaluated for their cytotoxicity activity against NCL-H460 lung cancer cells in vitro and showed moderate activity with IC50 value of 20.05 μg/mL.
| Item Type: | Article |
|---|---|
| Uncontrolled Keywords: | β-sitosterol; caulerpin; Halimeda cylindracea; NCL-H460 lung cancer cells |
| Divisions (Program Studi): | Fakultas Matematika dan Ilmu Peng. Alam > Ilmu Kimia |
| Depositing User: | Dr. Iskandar Iskandar |
| Date Deposited: | 15 Sep 2022 03:07 |
| Last Modified: | 15 Sep 2022 03:07 |
| URI: | http://repository.unhas.ac.id:443/id/eprint/19079 |
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