Hasanuddin University

Phytochemical screening and antibacterial activity of crude extracts fromJatropha curcas, Linn against histamine-forming bacteria

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dc.contributor.author Firdaus
dc.contributor.author Laga, Amran
dc.contributor.author Setha, Beni
dc.contributor.author Mahendradatta, Meta
dc.date.accessioned 2017-11-14T08:29:23Z
dc.date.available 2017-11-14T08:29:23Z
dc.date.issued 2014-02-03
dc.identifier.issn 2229-712X
dc.identifier.uri http://repository.unhas.ac.id/handle/123456789/26230
dc.description This article discuss about screening of secondary metabolite from extract of Jatropha curcas and their potency as antibacterial en_US
dc.description.abstract This study aims to analyze the phytochemical screening and antibacterial activity of leaves extract of Jatropha curcas against histamine forming bacteria, and determine of minimum inhibitory concentration. The extraction process is done by maceration method using hexane, chloroform, ethyl acetate and methanol. The extract was obtained continued by antibacterial activity test against histamine-forming bacteria. Concentration all extract of J. curcas is 1%, 10%, 20%, and 30% (w / v). Positive control using synthetic antibiotic ampicillin and negative controls used dimethyl sulfoxide (DMSO). The results of phytochemical screening showed that ethyl acetate and methanol extracts containing 5 secondary metabolites, while the hexane and chloroform containing only 2 secondary metabolites. Antibacterial activity test showed that the negative control and positive control do not provide inhibition against test bacteria. All types of extracts with concentrations of 1% to 30% (w / v) gave inhibition against test bacteria. The diameter of the inhibition of K. pneumoniae and C. perfringens for all jatropha leaf extract at a concentration of 1% (w / v) did not show any significant difference to the concentration of 10%. Lowest MIC (0.10% w / v) there at the ethyl acetate extract (E3) and methanol (E4) for the bacteria C. perfringens. en_US
dc.language.iso en en_US
dc.publisher Open access journal en_US
dc.relation.ispartofseries Vol. 67;
dc.subject Phytochemical, Antibacterial, Jatropha curcas, Histamine forming-bacteria en_US
dc.title Phytochemical screening and antibacterial activity of crude extracts fromJatropha curcas, Linn against histamine-forming bacteria en_US
dc.type Article en_US
dc.UNHAS.email firdaus@unhas.ac.id en_US
dc.UNHAS.Fakultas FMIPA en_US
dc.UNHAS.Prodi Kimia en_US
dc.UNHAS.idno 196009091988101001 en_US

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